{ "_id": "6a22b40f0ef520ea2f58d80d", "Package": "inferMM", "Type": "Package", "Title": "Variance-Aware Michaelis-Menten Estimation and Inference", "Version": "0.0.3", "Authors@R": "c(\nperson(given = \"Mijeong\", family = \"Kim\", role = c(\"aut\", \"cre\"),\nemail = \"m.kim@ewha.ac.kr\"),\nperson(given = \"Minkyoung\", family = \"Cha\", role = \"aut\"),\nperson(given = \"Ah Young\", family = \"Jeong\", role = \"aut\")\n)", "Description": "Variance-aware Michaelis-Menten estimation, model\nscreening, grouped enzyme-kinetic analyses, and clustered\nrepeated-measurement workflows. The package implements\nprofile-score estimators under working variance functions,\ntogether with a lightweight cluster-aware working-covariance\nextension, Wald and bootstrap confidence intervals, prediction\nutilities, and simulation helpers. Related methodology is\ndiscussed by Kim and Ma (2012) ,\nKim (2023) , and Ma and Genton (2010)\n.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "true", "Roxygen": "list(markdown = TRUE)", "VignetteBuilder": "knitr", "Config/testthat/edition": "3", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-05 11:29:24 UTC", "User": "root" }, "Author": "Mijeong Kim [aut, cre], Minkyoung Cha [aut], Ah Young Jeong\n[aut]", "Maintainer": "Mijeong Kim ", "Repository": "https://mijeong-kim.r-universe.dev", "Date/Publication": "2026-06-04 23:24:33 UTC", "RemoteUrl": "https://github.com/mijeong-kim/infermm", "RemoteRef": "HEAD", "RemoteSha": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "MD5sum": "903ab747d1b11c79dbb22fcf09ff8da6", "_user": "mijeong-kim", "_type": "src", "_file": "inferMM_0.0.3.tar.gz", "_fileid": "743943ffed02db86fdbceb089f114caa4fb7b526731363e29db5d099998e8d5f", "_filesize": 246543, "_sha256": "743943ffed02db86fdbceb089f114caa4fb7b526731363e29db5d099998e8d5f", "_created": "2026-06-05T11:29:24.000Z", "_published": "2026-06-05T11:33:35.361Z", "_distro": "noble", "_jobs": [ { "job": 79718518323, "time": 119, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "7435488197" }, { "job": 79718518313, "time": 120, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7435488411" }, { "job": 79718518302, "time": 102, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "7435515466" }, { "job": 79718518303, "time": 104, "config": "macos-release-arm64", "r": "4.6.0", "check": "OK", "artifact": "7435515957" }, { "job": 79718085436, "time": 181, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7435453916" }, { "job": 79718518278, "time": 84, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7435478434" }, { "job": 79718518365, "time": 98, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "7435482625" }, { "job": 79718518316, "time": 94, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "7435481138" }, { "job": 79718518318, "time": 77, "config": "windows-release", "r": "4.6.0", "check": "OK", "artifact": "7435476367" } ], "_buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/mijeong-kim/infermm", "_commit": { "id": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "author": "Mijeong Kim <46308782+mijeong-kim@users.noreply.github.com>", "committer": "GitHub ", "message": "Add files via upload", "time": 1780615473 }, "_maintainer": { "name": "Mijeong Kim", "email": "m.kim@ewha.ac.kr", "login": "mijeong-kim", "description": "", "uuid": 46308782 }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.1.0", "role": "Depends" }, { "package": "graphics", "role": "Imports" }, { "package": "grDevices", "role": "Imports" }, { "package": "stats", "role": "Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "testthat", "version": ">= 3.0.0", "role": "Suggests" } ], "_owner": "mijeong-kim", "_selfowned": true, "_usedby": 0, "_updates": [ { "week": "2026-20", "n": 1 }, { "week": "2026-23", "n": 5 } ], "_tags": [], "_stars": 0, "_contributors": [ { "user": "mijeong-kim", "count": 6, "uuid": 46308782 } ], "_userbio": { "uuid": 46308782, "type": "user", "name": "Mijeong Kim" }, "_downloads": { "count": 136, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/inferMM" }, "_devurl": "https://github.com/mijeong-kim/infermm", "_searchresults": 0, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/inferMM.html", "extra/NEWS.html", "extra/NEWS.txt", "extra/readme.html", "extra/readme.md", "manual.pdf" ], "_homeurl": "https://github.com/mijeong-kim/infermm", "_realowner": "mijeong-kim", "_cranurl": true, "_releases": [ { "version": "0.0.2", "date": "2026-05-27" }, { "version": "0.0.3", "date": "2026-06-04" } ], "_exports": [ "cluster_mm", "fit_mm", "group_mm", "report_mm", "screen_mm", "simulate_mm_data", "variance_function" ], "_datasets": [ { "name": "alves_demo", "title": "Subset of the Alves Soil Enzyme Kinetics Data", "object": "infer_mm_demo_data", "class": [ "data.frame" ], "fields": [ "core", "depth", "enzyme", "temperature", "substrate_conc", "activity" ], "rows": 247, "table": true, "tojson": true }, { "name": "sdl_demo", "title": "Self-Driving Laboratory Michaelis-Menten Demo Data", "object": "infer_mm_demo_data", "class": [ "data.frame" ], "fields": [ "enzyme", "s_uM", "replicate", "v_uM_per_s", "v_uM_per_min" ], "rows": 168, "table": true, "tojson": true } ], "_help": [ { "page": "inferMM-package", "title": "inferMM: Variance-Aware Michaelis-Menten Estimation and Inference", "topics": [ "inferMM-package", "inferMM" ] }, { "page": "alves_demo", "title": "Subset of the Alves Soil Enzyme Kinetics Data", "topics": [ "alves_demo" ] }, { "page": "cluster_mm", "title": "Fit a Cluster-Aware Michaelis-Menten Model", "topics": [ "cluster_mm", "coef.cluster_mm", "confint.cluster_mm", "plot.cluster_mm", "predict.cluster_mm", "print.cluster_mm", "print.summary.cluster_mm", "summary.cluster_mm", "vcov.cluster_mm" ] }, { "page": "fit_mm", "title": "Fit a Variance-Aware Michaelis-Menten Model", "topics": [ "coef.fit_mm", "confint.fit_mm", "fit_mm", "plot.fit_mm", "predict.fit_mm", "print.fit_mm", "print.summary.fit_mm", "summary.fit_mm", "vcov.fit_mm" ] }, { "page": "group_mm", "title": "Fit Multiple Michaelis-Menten Curves by Group", "topics": [ "group_mm", "plot.group_mm", "print.group_mm" ] }, { "page": "report_mm", "title": "Print and Plot a Michaelis-Menten Fit", "topics": [ "report_mm" ] }, { "page": "screen_mm", "title": "Screen Working Variance Models", "topics": [ "print.screen_mm", "screen_mm" ] }, { "page": "sdl_demo", "title": "Self-Driving Laboratory Michaelis-Menten Demo Data", "topics": [ "sdl_demo" ] }, { "page": "simulate_mm_data", "title": "Simulate Michaelis-Menten Data", "topics": [ "simulate_mm_data" ] }, { "page": "variance_function", "title": "Create Working Variance Functions", "topics": [ "variance_function" ] } ], "_readme": "https://github.com/mijeong-kim/infermm/raw/HEAD/README.md", "_rundeps": [], "_vignettes": [ { "source": "infer-mm-workflow.Rmd", "filename": "infer-mm-workflow.html", "title": "A Workflow for Variance-Aware Michaelis-Menten Analysis", "engine": "knitr::rmarkdown", "headings": [ "Single-curve fitting", "Screening working variance models", "Grouped analyses", "Clustered repeated measurements", "Simulation" ], "created": "2026-05-13 06:53:07", "modified": "2026-06-04 23:19:30", "commits": 2 } ], "_score": 4, "_indexed": true, "_nocasepkg": "infermm", "_universes": [ "mijeong-kim" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.0.3", "date": "2026-06-05T11:31:18.000Z", "distro": "noble", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "478a671c12d54e7537c0d901ed0c89a4eda4ffcabaffdf2b58b2ab939e35d7f8", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.6.0", "os": "linux", "version": "0.0.3", "date": "2026-06-05T11:31:20.000Z", "distro": "noble", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "071bf61744efc854765ae4bea7f5064ca838f1386049ed034782cfcee03d83bb", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.5.3", "os": "mac", "version": "0.0.3", "date": "2026-06-05T11:32:56.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "bc53765b25ece67c74aff374a3dc5330f01f10728e75f346626e0733dce1cf28", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.6.0", "os": "mac", "version": "0.0.3", "date": "2026-06-05T11:32:59.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "0c78411d15ace43682136d851323de61cd350c61c64d62a192783500d682aa77", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.6.0", "os": "wasm", "version": "0.0.3", "date": "2026-06-05T11:31:07.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "4b009b850df30064fb0e277b624c143c861272fe45ab70605b320437c53697e0", "status": "success", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.7.0", "os": "win", "version": "0.0.3", "date": "2026-06-05T11:30:50.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "a2fd1e609a082b64b76b81683cb85131601efe9d6a4ce6647fc91c821337bca2", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.5.3", "os": "win", "version": "0.0.3", "date": "2026-06-05T11:30:44.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "d1c05f1ed5579511dd9b3065e9dedd4db1d31b2ee6a7b0eb517b8d7db62716c2", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" }, { "r": "4.6.0", "os": "win", "version": "0.0.3", "date": "2026-06-05T11:30:28.000Z", "commit": "c5b9905f05490b96cbcf019d1b4f2ef64b749571", "fileid": "96afb4feeaac96f7097e8860d9feee92512591877fb5b119e83dd4995d05d6d0", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/mijeong-kim/actions/runs/27012132797" } ] }